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Opening in 2006, this art museum and education center offers exhibitions and programs that explore the ongoing and historic human relationship with water. The museum began with a substantial collection of works by regional folk artists Leo and Marilyn Smith. The museum's collection has expanded significantly in the past decade, including works related to marine life by a number of American and European artists such as Monet, Renoir, Van Gogh, and Picasso. The museum is also home to one of only two surviving original versions of one of two surviving versions of George Washington Crossing the Delaware. These works and others are among the museum's five galleries.

The museum is located on the shore of the Mississippi River and surrounded by native marine wildlife.

The museum is located on the shore of the Mississippi River and surrounded by native marine wildlife.