Erected in 1819, Thornhill is the oldest home of a former Missouri governor in the state. The estate was the home of Frederick Bates who served as Missouri's second governor (1825) and territorial secretary for both the Louisiana and Missouri Territory. Bates also had two brothers in public service: Edward, who served as Abraham Lincoln's Attorney General, and James, Territorial Senator to the Arkansas Territory. From 1808 until 1824, Bates purchased land in the area along with enslaved persons whose labor enriched Bates and allowed him to expand his property to include the 1,000-acre farm known as Thornhill. The property was later occupied by the grandson of beer baron Adolphus Busch who donated the property to St. Louis County for use as a park and historic site.

Constructed in 1859-1860, this Greek Revival home got its name, "Mudd's Grove," from one of its first residents, Sarah Elizabeth and Henry T. Mudd. The couple lived in the home from 1865 to 1882, and they had seven children. Henry Mudd worked as a farmer but also served as county auditor, member of the Town Board of Kirkwood, curator of the University of Missouri, and in the Missouri State Legislature where he helped frame the state Constitution.

Since 1989, this historic plantation home known as White Haven has been managed by the National Park Service which offers exhibits and interpretive tours of the property. The ten-acre historic site includes the birth home of Julia Dent Grant as well as the home where she lived with her husband, Ulysses S. Grant. The property was owned by Colonel Frederick Dent who gifted a small portion of land to the Grants after their marriage. In recent years, interpretive efforts have focussed on the people who were enslaved by the Dent family, in addition to the estate and acreage that became the property of the future president upon his marriage. The couple moved to White Haven in 1854 and lived here until 1859. The outbreak of the Civil War led to Grant's appointment as a commander in the West, and his violent but successful military campaigns against Confederate forces led to his promotion to commanding general of Union forces at the end of 1863. Grant won election to the Presidency of the United States in 1868 and was reelected in 1872.

The Joseph Sappington Log House is a two-story log cabin that is thought to have been built in 1816. There are three rooms on the first floor, each room has its own chimney. The interior of these rooms has been restored and the logs are visible from the inside. Currently, the Sappington House Foundation is in negotiation with the city to be relocated to the same property as the Thomas Sappington House.

Designed by St. Louis architect George Ingham Barnett and built from 1850 to 1851, this two-story Italianate-style house includes a unique four-story watch tower and was built for layer and banker Louis Auguste Benoist. Benoist lived from 1803 to 1867 and built this home towards the final years of his life which was on the high point of his land which spanned more than 475 acres and he named Oakland Farms. Architect George Barnett also designed the historic Tower Grove House (1849) for Henry Shaw, Missouri Botanical Garden founder, and the Governor's Mansion in Jefferson City. The house now operates as the Oakland House Museum and serves as the home to the Affton Historical Society. It's also a popular spot for weddings and events.

The Chatillon-DeMenil Mansion, built in 1848 in the historic Benton Park neighborhood and one of the few remaining examples of Greek Revival architecture in St. Louis, provides an in-depth glimpse into the lives of two French families. The construction of the house spans two building programs undertaken by families of very different styles of living, yet each reflecting significant aspects of St. Louis' French cultural heritage. The house today serves as a house museum. Although many other houses were built throughout the city in the grand antebellum manner, the DeMenil House is the only remaining Greek Revival house of such monumental proportions in the City of St. Louis.

This museum is located in the birthplace and early childhood residence of Eugene Field *1850-1895), a popular author of children’s literature in the 19th century. Field's poems for children led to his rise in the literary world, and when he passed away at age 45, he was known as "the Children's Poet." In 1902, Mark Twain unveiled a plaque honoring Field that recognized this rowhouse as Field's birthplace. The remaining rowhomes was so well-known that In recent years, there has been greater emphasis on the life of Eugene's son Roswell Field, the attorney who formulated the legal strategy for Dred Scott's lawsuit for freedom before the Supreme Court. The house is a museum with a vast collection of historic toys, and it also serves as a place where visitors can learn about the Dred Scot case. The museum includes artifacts and items related to the era in which Roswell, Frances, and Eugene Field lived within its walls. The house features special exhibits, workshops, and conferences on civil rights, law and social justice. The museum was also offers displays related to Eugene Field's career and historic toys. Eugene Field came to be known as the “Children’s Poet” for his stories and poems, which include “Little Boy Blue” and “Wynken, Blynken and Nod.” The house was saved from demolition in 1934 due to its significance as the early boyhood home of Eugene Field, the “Children’s Poet” and Roswell Field’s son.

Since opening in 1943, the Campbell House Museum has served the greater St. Louis area as one of the nation’s premier historic property museums. The house served as a family home of Robert Campbell from 1851 to 1938. The Museum preserves not only the Campbell’s house, the family home of Robert Campbell—a prominent figure in the history of St. Louis and of the American West— but also the family’s collection of original furniture, fixtures, paintings, letters, objects , thousands of pages of family documents, and unique album of 60 interior photographs taken in the mid-1880s. In 2000, the Museum began a meticulous restoration project that returned the building to its opulent 1880s appearance, when the house was one of the centers of St. Louis society. The museum is considered to be one of the best preserved mid-Victorian house museums in the United States.

Bellefontaine Cemetery was established in 1850, becoming the first designed large-scale rural cemetery west of the Mississippi. The parcel reached its largest size, 336 acres, in 1865, the year the American Civil War ended (it stands at 314 acres today). Its design combines elements of the rural cemetery concept, modeled on Boston's 1831 Mount Auburn Cemetery (which was itself derived from Père Lachaise cemetery in Paris) and the landscape-lawn movement, pioneered by Adolph Strauch in Cincinnati's Spring Grove Cemetery in the 1840s. Designed and originally supervised by Almerin Hotchkiss, the designer of Green-Wood Cemetery in Brooklyn, New York, the landscape features rolling hills, trees, and man-made lakes, around which many imposing funerary monuments and mausoleums are arranged. Over 87,000 people are interred here, many of them in unmarked gravesites. The cemetery was entered in the National Register of Historic Places in August 2014. The cemetery is also an accredited arboretum, the only one in St. Louis.